Low thyroid function is one of the most commonly missed diagnoses in conventional medicine — often dismissed when standard labs fall within "normal range."
Exhausted, cold and gaining weight, yet told your thyroid is “fine”?
You’re not alone. Many of Dr. Kellman’s patients arrive after years of unexplained symptoms and being told their labs look normal. His job is to keep looking.
Standard TSH testing has a wide "normal" range that can overlook meaningful dysfunction. Many patients with clear symptoms are told their labs are fine.
Dr. Kellman uses a highly precise thyroid test to detect low thyroid function more definitively — a test often unknown and underutilized elsewhere — combined with the gut-thyroid connection central to Microbiome Medicine.
Hypothyroidism, or low thyroid, means the thyroid isn't producing enough thyroid hormone for the body's needs. Because thyroid hormone sets the pace of metabolism, low levels can slow almost everything: energy, digestion, temperature regulation, mood and thinking.

The TRH stimulation test
Normal TSH. Still feeling sick?
A standard TSH result is a single snapshot. The TRH stimulation test looks at how the signal from the brain to the thyroid responds, which can add information when symptoms and routine labs don’t match.
Raphael Kellman, MD · How the TRH test works →
Hypothyroidism is one of the most common hormone conditions in the United States:




Many cases are mild or “subclinical,” and symptoms can be subtle and easy to attribute to stress, aging or busy lives, which is part of why low thyroid so often goes unrecognized.
Because thyroid hormone affects nearly every system in the body, low thyroid can show up in many ways. Symptoms usually develop slowly, over months or years:
Having one or two of these doesn't mean you have low thyroid, but a combination of them, especially fatigue, weight change, feeling cold and brain fog, is a good reason to have your thyroid checked. About thyroid testing →
Some people have a mildly raised TSH while free T4 is still normal. This subclinical pattern doesn't always need treatment, but it deserves monitoring and a careful look at symptoms, antibodies and how results change over time.
Thyroid hormone helps set the pace of the gut. When it's low, digestion can slow, contributing to constipation and bloating, and research has linked hypothyroidism with a higher rate of small intestinal bacterial overgrowth (SIBO). This connection is one reason Dr. Kellman evaluates the gut and the thyroid together. Learn about bloating →
For details on testing, including TRH stimulation testing, see thyroid evaluation and treatment and the TRH stimulation test.

Thyroid issues are most often caused by autoimmune attack (Hashimoto's disease), nutrient deficiencies, chronic stress, and gut microbiome imbalance, which can impair thyroid hormone conversion and regulation.
Common signs include persistent fatigue, weight gain resistant to diet and exercise, brain fog, hair thinning, cold intolerance, and low mood.
Standard TSH testing has a wide reference range that can miss meaningful dysfunction. More precise, comprehensive thyroid testing can reveal issues standard bloodwork overlooks.
Treatment may include bio-identical thyroid hormone therapy, addressing gut microbiome imbalance, and targeted nutrients — personalized to the root cause identified through advanced testing.
Yes. Low thyroid can slow digestion, which can contribute to constipation and bloating, and it has been linked with a higher rate of SIBO.
Usually TSH rises when the thyroid is underactive, but not always. In central hypothyroidism, for example, TSH may not rise as expected. A result inside the range also needs to be read alongside your symptoms, free T4 and your own earlier results.
Primary care doctors, internists and endocrinologists all treat hypothyroidism. Dr. Kellman is an internist whose practice has focused on thyroid and gut health for more than 25 years, particularly for patients who still feel unwell despite “normal” results.
Hypothyroidism affects about 1 in 10 people in the United States, according to a 2022 analysis of national survey and claims data. It is more common in women and in adults over 60.
Early signs are often subtle: fatigue, feeling cold, mild weight gain, dry skin, constipation and trouble concentrating. Because they develop slowly, they're easy to dismiss.
Sources: 1. Wyne KL et al. Hypothyroidism prevalence in the United States: a retrospective study combining NHANES and claims data, 2009–2019. J Endocr Soc. 2022;7(1):bvac172. 2. American Thyroid Association, General Information/Press Room (thyroid.org). 3. Canaris GJ et al. The Colorado Thyroid Disease Prevalence Study. Arch Intern Med. 2000;160(4):526–534. 4. University of Nebraska Medical Center news release on the Colorado study, Feb. 28, 2000. 5. Hollowell JG et al. Serum TSH, T4, and thyroid antibodies in the United States population (1988 to 1994): NHANES III. J Clin Endocrinol Metab. 2002;87(2):489–499.
“He's helped me tremendously with my thyroid issues. He figured it out when traditional doctors told me my thyroid was normal. Turns out it wasn't.”
Google review · Oct 2025
“I have been going to Dr. Kellman for many years, he's the only doctor I trust to understand and manage my thyroid issues.”
Google review · Oct 2023
“Expert advice for thyroid and related gut issues.”
Google review · Apr 2026
Reviews are shared exactly as written by patients on Google. Individual experiences vary.